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The Psychedelic Podcast

The Psychedelic Podcast connects you to the leaders and pioneers of the psychedelic renaissance. From deep healing to creativity, leadership to spirituality, business, health, human performance, relationships, sexuality, and even culture itself—every aspect of our world is being transformed by psychedelic medicines. Get an inspired, informed, balanced look into how these powerful medicines are already being safely and responsibly used to catalyze both personal and collective transformation. Whether you’re just curious or a seasoned psychonaut, or somewhere in between, you’ll get insightful, practical, cutting-edge conversations from the forefront of the psychedelic movement. Join us as we explore how psychedelics can be integrated into culture for the evolution of humanity.
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Now displaying: July, 2025
Jul 28, 2025

In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Dr. Vass Eliopoulos, co-founder of Longevity Health and a pioneer at the intersection of regenerative medicine, longevity science, and psychedelics.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-314/?ref=278

Dr. Vass shares his journey from emergency medicine to a proactive, prevention-based approach to health optimization for high performers.

Dr. Vass shares why today’s healthcare system fails to address the root causes of disease, the synergistic potential of psychedelics, stem cells, peptides, and hyperbaric oxygen therapy, and how chronic stress and inflammation underlie many modern conditions. He also outlines why psychedelics may be essential in reversing chronic inflammation and treating neurodegenerative diseases—and how prevention, not pathology, should guide the future of medicine.

Dr. Vassily Eliopoulos (Dr. Vass) is the Co-Founder and Chief Medical Officer of Longevity Health, a cutting-edge regenerative medicine clinic in Boulder, Colorado. A former ER physician and Peace Corps volunteer, Dr. Vass now helps high performers optimize their health through advanced diagnostics, regenerative therapies, and personalized plans. A black belt in Brazilian Jiu-Jitsu, avid climber, and kayaker, he brings deep experience in resilience and recovery to his clinical work.

Highlights:

  • Why Vass left emergency medicine for longevity health
  • COVID as a catalyst for self-directed wellness
  • The failure of “sick care” to promote true health
  • Psychedelics as first-line treatments for mental health
  • Chronic stress, inflammation, and disease progression
  • Synergies between psychedelics, stem cells, and peptides
  • Prevention vs. pathology in modern medicine
  • Neurodegeneration as chronic brain injury
  • Future directions for regenerative and psychedelic therapies

Curious about becoming a certified psychedelic coach? Join Paul F. Austin Thursday, July 31 2025, 10:00 AM PT for a free info session exploring the Psychedelic Coaching Institute’s Practitioner Certification Program—an immersive training that blends science, ceremony, and real-world coaching to help you lead others through lasting transformation. Learn More.

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Jul 25, 2025

Following our recent conversation with Dr. Robin Carhart-Harris on the neuroscience of SSRIs and psychedelics, this bonus episode takes the next step—focusing on clinical realities, tapering strategies, and patient safety.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-313b/?ref=278

Dr. Dave Rabin—a board-certified psychiatrist, neuroscientist, and co-founder of Apollo Neuro—joins Paul F. Austin for a candid, protocol-driven conversation. Together, they unpack why combining SSRIs with psychedelics can be dangerous, how to safely taper with support tools like ketamine and CBDA, and how to prepare clients for deeper psychedelic work.

If you’re a facilitator, therapist, or simply someone navigating antidepressants and interested in microdosing, this episode offers practical, medically-grounded insights.

Highlights:

  • How SSRIs blunt emotional range and alter awareness
  • The neuroscience of serotonin and psychedelic receptors
  • Serious risks of serotonin syndrome when mixing with SSRIs
  • Ketamine’s role in tapering and unlocking neuroplasticity
  • Practical tools to regulate the nervous system during SSRI withdrawal
  • Recommended psilocybin strains for sensitive or anxious clients
  • How long-term SSRI use may (or may not) affect psychedelic response
  • Safety-first protocols for psychedelic integration
  • The future of microdosing as a sustainable antidepressant approach

Episode Links:

Curious about becoming a certified psychedelic coach? Join Paul F. Austin Thursday, July 31 2025, 10:00 AM PT for a free info session exploring the Psychedelic Coaching Institute’s Practitioner Certification Program—an immersive training that blends science, ceremony, and real-world coaching to help you lead others through lasting transformation. Learn More.

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Jul 21, 2025

In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Dr. Dan Engle—psychiatrist, neurologist, and integrative medicine pioneer—for a profound discussion on psychedelics, brain health, and healing.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-313/?ref=278

Dr. Dan shares his personal journey through traumatic brain injuries and recovery through both Western neurology and indigenous plant medicine traditions. They explore neuroplasticity vs. neurogenesis, ibogaine’s potential in brain injury recovery, and how belief, awe, and prayer shape healing outcomes. Dr. Dan also reflects on lessons psychiatry can learn from shamanic practice—highlighting the importance of service, community, and ceremony in catalyzing transformation.

Dr. Dan Engle is a psychiatrist whose work bridges regenerative medicine, psychedelic research, integrative spirituality, and peak performance. He is founder of Full Spectrum Medicine, a psychedelic integration platform, and Thank You Life, a nonprofit expanding access to psychedelic therapies. He is author of The Concussion Repair Manual and A Dose of Hope: A Story of MDMA-Assisted Psychotherapy.

Episode Highlights: 

  • Healing from traumatic brain injury
  • Iboga vs. Ibogaine: Benefits and risks
  • Neuroplasticity vs. neurogenesis explained
  • The science of awe and belief in healing
  • Shamanic lessons for modern psychiatry
  • Critical learning periods after psychedelic sessions
  • Psychedelics as clarogens and renewing agents
  • The placebo effect and collective service
  • Texas legislation and Ibogaine research

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Jul 18, 2025

In this episode of The Psychedelic Podcast, Paul F. Austin is joined by renowned neuroscientist Dr. Robin Carhart-Harris and microdosing policy advocate John Downs for a replay of a live event originally held on June 10th, Microdosing vs. SSRIs: What’s Happening in the Brain and Why It Matters.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-312b/?ref=278

Together, they explore the scientific distinctions between SSRIs and psychedelics, focusing on neuroimaging, brain entropy, emotional processing, and the REBUS model. Dr. Carhart-Harris shares key insights from landmark studies on psilocybin therapy and discusses the evidence (and limitations) around microdosing. John Downs closes the conversation with an update on the Microdosing Collective’s efforts to shift policy and expand access.

Robin Carhart-Harris, PhD is a neuropharmacologist, psychologist, and Ralph Metzner Distinguished Professor in Neurology and Psychiatry at the University of California, San Francisco. He leads the Psychedelics Division at UCSF’s Neuroscape and formerly founded and led the Centre for Psychedelic Research at Imperial College London.

John Downs is Executive Director of the Microdosing Collective, advocating for responsible policy reform and legal access to microdosing. With 25 years’ experience in sales, business development, and emerging markets, John helps individuals optimize mindset, performance, and purpose.

Episode Highlights:

  • Why SSRIs blunt, while psychedelics reset emotional processing
  • How psilocybin compares to antidepressants in clinical trials
  • Brain entropy, plasticity, and the REBUS model explained
  • The role of the default mode network in mental health
  • Why microdosing research is still so limited
  • Ketamine vs. psilocybin: differences in brain mechanisms
  • Is serotonin syndrome a real microdosing risk?
  • Can psychedelics reverse long-term SSRI effects?
  • The Microdosing Collective’s mission for policy reform
  • What Robin Carhart-Harris’ upcoming book will explore

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Jul 14, 2025

In this episode of The Psychedelic Podcast, host Paul F. Austin welcomes back J. Ashley T. Booth, LCSW, MS—a longtime friend, therapist, and psychedelic pioneer.

Find full show notes and links here: https://thethirdwave.co/podcast/episode-312/?ref=278

Ashley shares her journey from community activism to clinical work with ketamine and MDMA, and her new illustrated guide to IFS, Quieting the Storm Within.

J. Ashley T. Booth, LCSW, MS has led the Southern California Psychedelic Society, served as MAPS trial coordinator for MDMA-assisted PTSD therapy, co-founded a ketamine clinic, and offers IFS, Hakomi, integration, and harm reduction training. Her illustrated picture book introduces IFS concepts through visuals and metaphor.

Highlights:

  • Ashley’s 8‑year evolution from community to clinical work
  • The origin and intent behind Quieting the Storm Within
  • Clouds & sun: A visual metaphor for the internal landscape<
  • How IFS helps reframe so-called “bad” behaviors with compassion
  • Preparing for psychedelic journeys using parts work
  • Somatic memory and frozen parts in the body
  • Why low‑dose, psycholytic sessions create safer containers
  • Clinical nuances: Ketamine vs. MDMA for specific inner parts
  • The role of protector parts, consent, and titration in therapy
  • Integrating survival strategies into resilience and wholeness

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These show links may contain affiliate links. Third Wave receives a small percentage of the product price if you purchase through the above affiliate links.

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Jul 7, 2025

In this episode of The Psychedelic Podcast, Paul F. Austin welcomes anthropologist and author Dr. Manvir Singh to explore the enduring power of shamanism as a psychological and cultural technology.

Find full show notes and links here:
https://thethirdwave.co/podcast/episode-311/?ref=278

Singh discusses insights from his fieldwork with the Mentawai people and Amazonian Yopo shamans, explaining how ritual, performance, and belief help people manage uncertainty and catalyze healing. Together with Paul, he examines the contested history of ancient psychedelic use, the risks of neo-shamanic narratives, and the deep psychological roots of sacred ceremony.

Dr. Manvir Singh is an assistant professor of anthropology at the University of California, Davis. He holds a BA from Brown University and a PhD in human evolutionary biology from Harvard. His writing has appeared in The New Yorker, Wired, The Guardian, and top academic journals. His first book, Shamanism: The Timeless Religion, was published in 2025.

Highlights:

  • Shamanism as a psychological technology
  • Performance, otherness, and credibility in healing
  • Yopo, bufotenine, and entheogenic archaeology
  • Why ancient psychedelic use is hard to verify
  • The tension between tradition and neo-shamanism
  • What happens when ceremony loses its context

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These show links may contain affiliate links. Third Wave receives a small percentage of the product price if you purchase through the above affiliate links.

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