While a PhD researcher at Imperial College London, Mendel Kaelen investigated the brain mechanisms of classic psychedelic drugs and their effects on music-perception and music-evoked emotion. After a year off spent integrating his ayahuasca experiences in the Amazon, Mendel completed his Master’s Degree before founding Wavepaths, an algorithmic music system that unifies immersive arts, psychotherapies, and intelligent technologies into new models of care. In this episode, Mendel and Paul explore the beauty of randomness, the healing potential of psychedelics, our debt to primal sound, and the power of music to make meaning.